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Many tumors in one: a daunting therapeutic prospect.

TitleMany tumors in one: a daunting therapeutic prospect.
Publication TypeJournal Article
Year of Publication2011
AuthorsEne CI, Fine HA
JournalCancer Cell
Volume20
Issue6
Pagination695-7
Date Published2011 Dec 13
ISSN1878-3686
Abstract

In this issue of Cancer Cell, Snuderl and coworkers demonstrate intratumoral genetic heterogeneity in glioblastoma based on in situ amplification of distinct genomic loci within individual cells in a mutually exclusive pattern. These findings may herald trouble for current targeted therapies but provide insights for future treatment strategies.

DOI10.1016/j.ccr.2011.11.018
Alternate JournalCancer Cell
PubMed ID22172718