Submitted by jar2845 on March 18, 2019 - 1:11pm
Title | Glioma stem cells: not all created equal. |
Publication Type | Journal Article |
Year of Publication | 2009 |
Authors | Fine HA |
Journal | Cancer Cell |
Volume | 15 |
Issue | 4 |
Pagination | 247-9 |
Date Published | 2009 Apr 07 |
ISSN | 1878-3686 |
Keywords | Animals, Brain Neoplasms, Cell Differentiation, Glioma, Humans, Neoplastic Stem Cells, Transforming Growth Factor beta |
Abstract | A growing body of evidence suggests that only a small subpopulation of malignant glioma cells have true tumorigenic potential. A study by PeƱuelas et al. in this issue of Cancer Cell demonstrates that TGF-beta can stimulate self-renewal and inhibit differentiation in a proportion of these glioma-initiating cells. |
DOI | 10.1016/j.ccr.2009.03.010 |
Alternate Journal | Cancer Cell |
PubMed ID | 19345322 |