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Glioma stem cells: not all created equal.

TitleGlioma stem cells: not all created equal.
Publication TypeJournal Article
Year of Publication2009
AuthorsFine HA
JournalCancer Cell
Volume15
Issue4
Pagination247-9
Date Published2009 Apr 07
ISSN1878-3686
KeywordsAnimals, Brain Neoplasms, Cell Differentiation, Glioma, Humans, Neoplastic Stem Cells, Transforming Growth Factor beta
Abstract

A growing body of evidence suggests that only a small subpopulation of malignant glioma cells have true tumorigenic potential. A study by PeƱuelas et al. in this issue of Cancer Cell demonstrates that TGF-beta can stimulate self-renewal and inhibit differentiation in a proportion of these glioma-initiating cells.

DOI10.1016/j.ccr.2009.03.010
Alternate JournalCancer Cell
PubMed ID19345322