Publications

1.Detailed longitudinal sampling of glioma stem cells in situ reveals Chr7 gain and Chr10 loss as repeated events in primary tumor formation and recurrence. Baysan M, Woolard K, Cam MC, Zhang W, Song H, Kotliarova S, Balamatsias D, Linkous A, Ahn S, Walling J, Belova GI, Fine HA. Int J Cancer. 2017 Nov 15;141(10):2002-2013.

2.A Core Regulatory Circuit in Glioblastoma Stem Cells Links MAPK Activation to a Transcriptional Program of Neural Stem Cell Identity. Riddick G, Kotliarova S, Rodriguez V, Kim HS, Linkous A, Storaska AJ, Ahn S, Walling J, Belova G, Fine HA. Sci Rep. 2017 Mar 3;7:43605.

3.New strategies in glioblastoma: exploiting the new biology. Fine HA. Clin Cancer Res. 2015 May 1;21(9):1984-8.

4.Master regulators, regulatory networks, and pathways of glioblastoma subtypes. Bozdag S, Li A, Baysan M, Fine HA. Cancer Inform. 2014 Oct 15;13(Suppl 3):33-44.

5.Identification of molecular pathways facilitating glioma cell invasion in situ. Nevo I, Woolard K, Cam M, Li A, Webster JD, Kotliarov Y, Kim HS, Ahn S, Walling J, Kotliarova S, Belova G, Song H, Bailey R, Zhang W, Fine HA. PLoS One. 2014 Nov 3;9(11):e111783.

6.Timing (and biology) are everything. Fine HA. Neuro Oncol. 2014 Nov;16(11):1431-2.

7.Molecular characterizations of glioblastoma, targeted therapy, and clinical results to date. Bastien JI, McNeill KA, Fine HA. Cancer. 2015 Feb 15;121(4):502-16.

8.Micro-environment causes reversible changes in DNA methylation and mRNA expression profiles in patient-derived glioma stem cells. Baysan M, Woolard K, Bozdag S, Riddick G, Kotliarova S, Cam MC, Belova GI, Ahn S, Zhang W, Song H, Walling J, Stevenson H, Meltzer P, Fine HA. PLoS One. 2014 Apr 11;9(4):e94045.

9.Age-specific signatures of glioblastoma at the genomic, genetic, and epigenetic levels. Bozdag S, Li A, Riddick G, Kotliarov Y, Baysan M, Iwamoto FM, Cam MC, Kotliarova S, Fine HA. PLoS One. 2013 Apr 29;8(4):e62982.

10.Histone demethylase Jumonji D3 (JMJD3) as a tumor suppressor by regulating p53 protein nuclear stabilization. Ene CI, Edwards L, Riddick G, Baysan M, Woolard K, Kotliarova S, Lai C, Belova G, Cam M, Walling J, Zhou M, Stevenson H, Kim HS, Killian K, Veenstra T, Bailey R, Song H, Zhang W, Fine HA. PLoS One. 2012;7(12):e51407.

11.G-cimp status prediction of glioblastoma samples using mRNA expression data. Baysan M, Bozdag S, Cam MC, Kotliarova S, Ahn S, Walling J, Killian JK, Stevenson H, Meltzer P, Fine HA. PLoS One. 2012;7(11):e47839.

12.Gliomagenesis arising from Pten- and Ink4a/Arf-deficient neural progenitor cells is mediated by the p53-Fbxw7/Cdc4 pathway, which controls c-Myc. Kim HS, Woolard K, Lai C, Bauer PO, Maric D, Song H, Li A, Kotliarova S, Zhang W, Fine HA. Cancer Res. 2012 Nov 15;72(22):6065-75.

13.SnapShot: glioblastoma multiforme. Kotliarova S, Fine HA. Cancer Cell. 2012 May 15;21(5):710-710.e1.
Many tumors in one: a daunting therapeutic prospect. Ene CI, Fine HA. Cancer Cell. 2011 Dec 13;20(6):695-7.

14.Integration and analysis of genome-scale data from gliomas. Riddick G, Fine HA. Nat Rev Neurol. 2011 Jul 5;7(8):439-50.

15.Glioma stem cells: better flat than round. Woolard K, Fine HA. Cell Stem Cell. 2009 Jun 5;4(6):466-7.

16.SSEA-1 is an enrichment marker for tumor-initiating cells in human glioblastoma. Son MJ, Woolard K, Nam DH, Lee J, Fine HA. Cell Stem Cell. 2009 May 8;4(5):440-52.

17.Glioma stem cells: not all created equal. Fine HA. Cancer Cell. 2009 Apr 7;15(4):247-9.

18.Unsupervised analysis of transcriptomic profiles reveals six glioma subtypes. Li A, Walling J, Ahn S, Kotliarov Y, Su Q, Quezado M, Oberholtzer JC, Park J, Zenklusen JC, Fine HA. Cancer Res. 2009 Mar 1;69(5):2091-9.

19.Correlation analysis between single-nucleotide polymorphism and expression arrays in gliomas identifies potentially relevant target genes. Kotliarov Y, Kotliarova S, Charong N, Li A, Walling J, Aquilanti E, Ahn S, Steed ME, Su Q, Center A, Zenklusen JC, Fine HA. Cancer Res. 2009 Feb 15;69(4):1596-603.

20.Glycogen synthase kinase-3 inhibition induces glioma cell death through c-MYC, nuclear factor-kappaB, and glucose regulation. Kotliarova S, Pastorino S, Kovell LC, Kotliarov Y, Song H, Zhang W, Bailey R, Maric D, Zenklusen JC, Lee J, Fine HA. Cancer Res. 2008 Aug 15;68(16):6643-51.